Jin WB, Li TT, Huo D, Qu S, Li XV, Arifuzzaman M, Lima SF, Shi HQ, Wang A, Putzel GG, Longman RS, Artis D, Guo CJ: Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome. Cell 2022, 185(3):547.

Lima SF, Gogokhia L, Viladomiu M, Chou L, Putzel G, Jin WB, Pires S, Guo CJ, Gerardin Y, Crawford CV, Jacob V, Scherl E, Brown SE, Hambor J, Longman RS: Transferable Immunoglobulin A–Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation. Gastroenterology 2022, 162(1):166.

Fischbach MA, Guo CJ, Voigt CA, Chang FY, Clardy J, Wyche T: Compositions and methods for modulating protease activity (patent).

Viladomiu M, Metz ML, Lima SF, Jin WB, Chou L, JRI Live Cell Bank, Guo CJ, Diehl GE, Simpson KW, Scherl EJ, Longman RS: Adherent-invasive E. coli metabolism of propanediol in Crohn’s disease regulates phagocytes to drive intestinal inflammation. Cell Host Microbe 2021, 29(4):607.

Guo CJ: Immune activation kickstarts the gut microbiota (preview). Cell Host Microbe 2021, 29(3):318.

Guo CJ: Modulating microbiome metabolites in vivo (award essay). Science 2020, 369:6500.

Finabashi M*, Grove TL*, Pascal V, Varma Y, McFadden ME, Brown LC, Guo CJ, Medema MH, Almo SC#, Fischbach MA#: A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Nature 2020, 582:566.

Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru J, Hambor J, Rudensky, AY : Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature 2020, 581:475.

Guo CJ, Allen BM, Hiam KJ, Dodd D, Treuren WV, Higginbottom S, Sonnenburg JL, Spitzer M#, Fischbach MA# : Depletion of microbiome-derived molecules in the host using Clostridium genetics. Science 2019, 366:6471.

Sun WW, Romsdahl J, Guo, CJ, Wang CC: Genome-based deletion analysis in Aspergillus terreus reveals the acetylaranotin bis-thiomethyltransferase gene. Fungal Genet Biol 2018, 119:1.

Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL: Microbial Transplantation with Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. Circ Res 2018, 123 (10):1164.

Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Masanori F, Taketani M, Donia MS, Nayfech S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voight CA, Fischbach MA: Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases. Cell 2017, 168: 517-526.

van Dijk JW, Guo CJ, Wang CC: Engineering Fungal Nonribosomal Peptide Synthetase-like Enzymes by Heterologous Expression and Domain Swapping. Org Lett 2016, 18(24): 6236.

Oakley CE, Ahuja M, Sun WW, Entwistle R, Akashi T, Yaegashi J, Guo CJ, Cerqueira GC, Wortman JR, Wang CC, Chiang YM, Oakley BR: Discovery of McrA, a Master Regulator of Aspergillus Secondary Metabolism. Mol Microbiol 2016, 103: 347.

Sun WW*, Guo CJ*, Wang CC: Characterization of the Product of a Nonribosomal Peptide Synthetase-like (NRPS-like) Gene Using the Doxycycline Dependent Tet-On System in Aspergillus terreus . Fungal Genet Biol 2016, 89: 84-88.

Barkal LJ*, Theberge AB*, Guo CJ*, Spraker J, Rappert L, Berthier J, Brakke KA, Wang CC, Beebe DJ, Keller NP, Berthier E, Microbial Metabolomics in Open Microscale Platforms. Nat Commun 2016, 7:10610. doi: 10.1038/ncomms10610.

Guo CJ, Sun WW, Bruno KS, Oakley BR, Keller NP, Wang CC: Spatial Regulation of a Common Precursor from Two Distinct Genes Generates Metabolite Diversity. Chem Sci 2015, 6(10): 5913-5921.

Gao YQ, Guo CJ, Zhang Q, Zhou WM, Gao JM, Wang CC: Asperaculanes A-F, Six Sesquiterpenoids from the Fungus Aspergillus aculeatus. Molecules 2014, 20(1): 325-334.

Guo CJ, Wang CC: Recent Advances in Genome Mining of Secondary Metabolites in Aspergillus terreus. Front Microbiol 2014, 5:717. doi: 10.3389/fmicb.2014.00717.

Guo CJ*, Sun WW*, Bruno KS, Wang CC: Molecular Genetic Characterization of Terreic Acid Pathway in Aspergillus terreus. Org Lett 2014, 16(20): 5250-5253.

Wiemann P, Guo CJ, Palmer JM, Wang CC, Keller NP: Prototype of an Intertwined Secondary Metabolite Supercluster. Proc Natl Acad Sci U.S.A. 2013, 110(42): 17065-17070.

Guo CJ, Knox BP, Sanchez JF, Chiang YM, Bruno KS, Wang CC: Application of an Efficient Gene Targeting System Linking Secondary Metabolites to Their Biosynthetic Genes in Aspergillus terreus. Org Lett 2013, 15(14): 3562-3565.

Berthier, E*, Lim FY*, Deng Q, Guo CJ, Kontoyiannis DP, Wang CC, Rindy J, Beebe DJ, Huttenlocher A, Keller NP: Low-volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites. PLoS Pathog 2013, 9(4): e1003289.

Guo CJ, Yeh HH, Chiang YM, Sanchez JF, Chang SL, Bruno KS, Wang CC: Biosynthetic Pathway for the Epipolythiodioxopiperazine Acetylaranotin in Aspergillus terreus Revealed by Genome-based Deletion Analysis. J Am Chem Soc 2013, 135(19): 7205-7213.

Guo CJ, Knox BP, Chiang YM, Lo HC, Sanchez JF, Lee KH, Oakley BR, Bruno KS, Wang CC: Molecular Genetic Characterization of a Cluster in A. terreus for Biosynthesis of the Meroterpenoid Terretonin. Org Lett 2012, 14(22): 5684-5687.

Lo HC, Entwistle R, Guo CJ, Ahuja M, Szewczyk E, Hung JH, Chiang YM, Oakley BR, Wang CC: Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans. J Am Chem Soc 2012, 134(10): 4709-4720.

Guo CJ, Ren Y, Qin YL, Zhang Q: The Synthesis and Biological Evaluation of 10-O-dialkylaminoethyl Ginkgolide B as Platelet-Activating Factor Antagonist. J Asian Nat Prod Res 2008, 10(9-10):989-992.

*:Co-first;#:Co-corresponding.